The Salk Institute article refers to this science paper published in Circulation Research: SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2.
This paper is the first to document the mechanism by which spike proteins — even ones lacking an active viral component — cause vascular destruction by binding to ACE2 receptors and inhibiting the function of cellular mitochondria.
From the paper:
SARS-CoV-1 [Spike] protein promotes lung injury by decreasing the level of ACE2 in the infected lungs. In the current study, we show that S protein alone can damage vascular endothelial cells (ECs) by downregulating ACE2 and consequently inhibiting mitochondrial function.
Also from the paper:
We next studied the impact of S protein on mitochondrial function. Confocal images of ECs treated with S1 protein revealed increased mitochondrial fragmentation, indicating altered mitochondrial dynamics…
Moreover, ACE2-L overexpression caused increased basal acidification rate, glucose-induced glycolysis, maximal glycolytic capacity, and glycolytic reserve (Figure [D], ii). Also, ECs incubated with S1 protein had attenuated mitochondrial function but increased glycolysis, when compared with control cells treated with IgG…
…our data reveals that S protein alone can damage endothelium, manifested by impaired mitochondrial function and eNOS activity but increased glycolysis. It appears that S protein in ECs increases redox stress which may lead to AMPK deactivation, MDM2 upregulation, and ultimately ACE2 destabilization.
The study, obviously authored by a pro-vaccine organization, then says that “vaccination-generated antibodies” may protect the body from the spike protein. Thus, the paper is essentially saying (paraphrased): “The spike protein may cause enormous damage to the vascular system when a person is injected with that spike protein, and when that person’s immune system attacks the spike protein and neutralizes it, the damage may be halted.”
In other words, the human immune system is trying to protect the patient from the damage caused by the vaccine, before the patient is killed by the adverse reactions.
Put another way, any person who actually survives the covid vaccine only does so because their innate immune system is protecting them from the vaccine, not with the vaccine. The vaccine is the weapon. Your immune system is your defense.